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All stimulants act to enhance the extracellular concentrations of dopamine, norepinephrine, and serotonin. Stimulant prescription drugs can block the transport of these neurotransmitters.
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This, coupled with crop reductions in Bolivia and Peru, produced Colombia the country with the most important area of coca underneath cultivation after the mid-nineteen nineties. Coca developed for classic needs by indigenous communities, a use which remains to be present and it is permitted by Colombian rules, only tends to make up a small fragment of whole coca output, a lot of which happens to be employed for the illegal drug trade.[222]
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It contained website six mg copyright for every ounce of wine, but Vin Mariani which was to get exported contained 7.2 mg for each ounce, to compete with the upper copyright material of comparable beverages in America. A "pinch of coca leaves" was included in John Styth Pemberton's unique 1886 recipe for Coca-Cola, though the corporate commenced making use of decocainized leaves in 1906 once the Pure Foods and Drug Act was passed.
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